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ProductsBack/SARS-CoV-2-IN-13 [56961-10-5]
CgoaEWY7M_KELN2lAAAAABI_pbE809.png
CgoaEWY7M_KELN2lAAAAABI_pbE809.png
CgoaEWY7M_KELN2lAAAAABI_pbE809.png

SARS-CoV-2-IN-13 [56961-10-5]

Research Use Only
T60919
TargetMol Chemicals
Molecular Weight327.12
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SARS-CoV-2-IN-13 [56961-10-5]
  • Delivery Days Customer
    4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    SARS-CoV-2-IN-13
  • Molecular Formula
    C13H8Cl2N2O4
  • Molecular Weight
    327.12
  • Scientific Description
    SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay. It improves bioavailability and half-life when administered orally and is a potent SARS-CoV-2 inhibitor with an IC50 of 0.057 microM [1].
  • Shelf life instruction
    3 years
  • SMILES
    Oc1ccc(Cl)cc1C(=O)Nc1ccc(c(Cl)c1)[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.
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