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SARS-CoV-2-IN-14 [22203-98-1]
T60538
Overview
- SupplierTargetMol Chemicals
- Product NameSARS-CoV-2-IN-14 [22203-98-1]
- Delivery Days Customer4
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameSARS-CoV-2-IN-14
- Molecular FormulaC13H9Cl2NO2
- Molecular Weight282.12
- Scientific DescriptionSARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 microM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.
- Shelf life instruction3 years
- SMILESC(NC1=CC(Cl)=CC=C1)(=O)C2=C(O)C=CC(Cl)=C2
- Storage Instruction-20°C
- UNSPSC51202000
References
- Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022;235:114295.Read more