SARS-CoV-2-IN-14
T60538
CAS Number22203-98-1
Product group Chemicals
Molecular Weight282.12
Overview
- SupplierTargetMol Chemicals
- Product NameSARS-CoV-2-IN-14
- Delivery Days Customer4
- CAS Number22203-98-1
- Category SupplierChemical
- Chemical NameSARS-CoV-2-IN-14
- Molecular FormulaC13H9Cl2NO2
- Molecular Weight282.12
- Scientific DescriptionSARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 uM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.
- Shelf life instruction3 years
- SMILESC(NC1=CC(Cl)=CC=C1)(=O)C2=C(O)C=CC(Cl)=C2
- Storage Instruction-20°
- UNSPSC12352200
References
- Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022;235:114295.Read more