SARS-CoV-2-IN-60

Biorbyt

SARS-CoV-2-IN-60

10

Research Use Only

98.00%

C13H7Cl2F3N2O

335.11

SARS-CoV-2-IN-60 (compound 5a) is a specific, irreversible inhibitor of SARS-CoV-2 nsp16-nsp10 methyltransferase, competing with S-adenosylmethionine (SAM) and exhibiting an IC50 of 9 microM and a Ki of 26 microM. It binds to a novel pocket near the SAM-binding site on nsp16, suggesting potential as a pan-coronavirus therapeutic [1].

-20°C

12352200