SARS-CoV-2 Mpro-IN-9

MedChem Express

SARS-CoV-2 Mpro-IN-9

14

Research Use Only

C20H14N2O4

346.34

SARS-CoV-2 Mpro-IN-9 (compound c7) is a nonpeptidic, noncovalent SARS-CoV-2 M pro inhibitor ( IC 50 =0.085 microM), with improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. SARS-CoV-2 Mpro-IN-9 inhibits viral replication ( EC 50 =1.10 microM) in SARS-CoV-2-infected Vero E6 cells, while exhibits low cytotoxic effects ( CC 50 >50 microM) [1] .

O=C1N(C2=CC=CC=C2)C(C3=CC=CC=C3)=NC4=C1C(O)=C(O)C(O)=C4

12352200