SARS-CoV-2 nsp3-IN-1

MedChem Express

SARS-CoV-2 nsp3-IN-1

5

Research Use Only

98.0

C17H15N5O2

321.33

SARS-CoV-2 nsp3-IN-1 (Compound 15c) is a Mac1 ( SARS-CoV-2 nsp3 macrodomain ) inhibitor with the IC 50 value of 6.1 microM. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity. SARS-CoV-2 nsp3-IN-1 demonstrates notable selectivity for coronavirus macrodomains, especially towards SARS-CoV-2 Mac1 [1] .

OC([C@H](CC1=CNC2=C1C=CC=C2)NC3=NC=NC4=C3C=CN4)=O

-20°C,2°C to 8°C

12352200