SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)

KACTUS

SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)

9

Research Use Only

>95%

The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

-80°C

12352202