SARS-COV-2 Spike RBD (N501Y) Protein (COV-VM1BY)
COV-VM1BY
Product group Proteins
Overview
- SupplierKACTUS
- Product NameSARS-COV-2 Spike RBD (N501Y) Protein (COV-VM1BY)
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionThe ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202