SARS-CoV-2 Spike RBD (Omicron XBB) Protein (XBB-HM1BD)

KACTUS

SARS-CoV-2 Spike RBD (Omicron XBB) Protein (XBB-HM1BD)

9

Research Use Only

>95%

The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

-20°C or -80°C,-80°C

12352202