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SART3 antibody [C3], C-term

GTX107684
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSART3
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Overview

  • Supplier
    GeneTex
  • Product Name
    SART3 antibody [C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.52 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9733
  • Target name
    SART3
  • Target description
    spliceosome associated factor 3, U4/U6 recycling protein
  • Target synonyms
    DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb), spliceosome associated factor 3, U4/U6 recycling protein, HIV-1 Tat-interacting protein of 110kDa, PRP24 homolog, SART-3, hSART-3, p110 nuclear RNA-binding protein, squamous cell carcinoma antigen recognized by T cells 3, tat-interacting protein of 110 kDa
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15020
  • Protein Name
    Spliceosome associated factor 3, U4/U6 recycling protein
  • Scientific Description
    The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • El Fatimy R, Zhang Y, Deforzh E, et al. A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing. Mol Cancer. 2022,21(1):17. doi: 10.1186/s12943-022-01494-z
    Read this paper
  • Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
    Read this paper