ProductsBack/SATB1 antibody

SATB1 antibody

Name: SATB1 antibody
SKU: ORB66709_B48
Availability: BackOrder

ORB66709

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman, Mouse

TargetSATB1

Overview

Supplier
Biorbyt
Product Name
SATB1 antibody
Delivery Days Customer
16
Applications
Western Blot
Applications Supplier
WB:1:1000-1:5000 WB
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID6304
Target name
SATB1
Target description
SATB homeobox 1
Target synonyms
DEFDA; DNA-binding protein SATB1; KTZSL; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA)
Host
Rabbit
Protein IDQ01826
Protein Name
DNA-binding protein SATB1
Scientific Description
Rabbit polyclonal to SATB1.Special AT-rich sequence-binding protein 1 (SATB1) is a chromatin organizer and transcription factorthat integrates chromatin architecture with gene regulation. SATB1 binds to nuclear matrix/scaffoldassociatingAT-rich DNA sequences (MARs/SARs). It has been shown that SATB1 interacts withpromyelocytic leukemia protein (PML), and that SATB1 and PML function as a regulatory complexthat controls transcription by restructuring the dynamic chromatin-loop architecture. SATB1 isimplicated as a key regulator of the differentiation and activation of T cells. In cancer, SATB1 hasbeen shown to reprogram chromatin organization and the transcription profiles of breast tumors topromote growth and metastasis.
Reactivity
Human, Mouse
Storage Instruction
-20°C
UNSPSC
12352203

Inhibition of indoleamine 2,3-dioxygenase in mixed lymphocyte reaction affects glucose influx and enzymes involved in aerobic glycolysis and glutaminolysis in alloreactive T-cells. Eleftheriadis T et al., 2013 Dec, Hum Immunol
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