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Western blot analysis of extracts of various cell lines using SAV1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using SAV1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using SAV1 Polyclonal Antibody at dilution of 1:1000.

SAV1 Polyclonal Antibody

Research Use Only
E-AB-62507
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    SAV1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
  • UNSPSC
    12352203