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SB-200646A

SB-200646A

T22423
TargetMol Chemicals
CAS Number143797-62-0
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Product group Chemicals
Molecular Weight302.76
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SB-200646A
  • Delivery Days Customer
    14
  • CAS Number
    143797-62-0
  • Category Supplier
    Chemical
  • Chemical Name
    SB-200646A
  • Molecular Formula
    C15H15ClN4O
  • Molecular Weight
    302.76
  • Scientific Description
    SB-200646A is an orally active, selective antagonist of 5-HT2B/2C over 5-HT2A receptor with pKi of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646A exerts anxiolytic and electrophysiological properties in vivo.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.O=C(NC=1C=NC=CC1)NC=2C=CC3=C(C=CN3C)C2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Blackburn TP, Suzuki K, Ashby CR Jr. The acute and chronic administration of the 5-HT(2B/2C) receptor antagonist SB-200646A significantly alters the activity of spontaneously active midbrain dopamine neurons in the rat: An in vivo extracellular single cell study. Synapse. 2006 Jun 15;59(8):502-12.
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