SB 206553 [158942-04-2]

TargetMol Chemicals

SB 206553 [158942-04-2]

16

158942-04-2

Research Use Only

C17H16N4O

292.34

SB 206553 is a 5-HT2C inverse agonist that can attenuate methamphetamine-seeking behavior in rats. It exhibits activity for 5-HT2 receptor ligands with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B), and 7.8 nM (5-HT2C) in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors. SB 206553 can be used for research into psychostimulant abuse disorders [1].

C(NC=1C=CC=NC1)(=O)N2C=3C(=CC4=C(C3)C=CN4C)CC2

-20°C

12352200