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SB-277011

SB-277011

T12861
TargetMol Chemicals
CAS Number215803-78-4
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Product group Chemicals
Molecular Weight438.56
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SB-277011
  • Delivery Days Customer
    4
  • CAS Number
    215803-78-4
  • Category Supplier
    Chemical
  • Chemical Name
    SB-277011
  • Molecular Formula
    C28H30N4O
  • Molecular Weight
    438.56
  • Scientific Description
    SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
  • Shelf life instruction
    3 years
  • SMILES
    C(N[C@@H]1CC[C@@H](CCN2CC=3C(CC2)=CC(C#N)=CC3)CC1)(=O)C=4C5=C(N=CC4)C=CC=C5
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Southam E, Lloyd A, Jennings CA, Cluderay JE, Cilia J, Gartlon JE, Jones DN.Effect of the selective dopamine D3 receptor antagonist SB-277011-A on regional c-Fos-like expression in rat forebrain.Brain Res. 2007 May 29;1149:50-7. Epub 2007 Feb 28.
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