SB-590885 [405554-55-4] [405554-55-4]

MedChem Express

SB-590885

10

405554-55-4

CHEMICAL,general_chemicals_reagents

Research Use Only

99.77

C27H27N5O2

453.54

SB-590885 is a potent B-Raf inhibitor with a Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases.

O/N=C1CCC2=CC(C3=C(NC(C4=CC=C(C=C4)OCCN(C)C)=N3)C5=CC=NC=C5)=CC=C/12

-20°C, 3 years; 4°C, 2 years (Powder)

12352005