SB-612111
T36376
Overview
- SupplierTargetMol Chemicals
- Product NameSB-612111
- Delivery Days Customer107
- CAS Number371980-98-2
- Category SupplierChemical
- Chemical NameSB-612111
- Molecular FormulaC24H29Cl2NO
- Molecular Weight418.4
- Scientific DescriptionSB-612111 is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for u-, kappa- and delta-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model[1].
- Shelf life instruction3 years
- SMILESClC1=C(C2CCN(C[C@@H]3C[C@H](O)C=4C(CC3)=C(C)C=CC4)CC2)C(Cl)=CC=C1
- Storage Instruction-20°
- UNSPSC12352200