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SB-649868

SB-649868

T5498
TargetMol Chemicals
CAS Number380899-24-1
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Product group Chemicals
Molecular Weight477.55
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SB-649868
  • Delivery Days Customer
    4
  • CAS Number
    380899-24-1
  • Category Supplier
    Chemical
  • Chemical Name
    SB-649868
  • Molecular Formula
    C26H24FN3O3S
  • Molecular Weight
    477.55
  • Scientific Description
    SB-649868 (GSK649868) is a potent and selective orally active antagonist of orexin(pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    C(=O)(C1=C(SC(C)=N1)C2=CC=C(F)C=C2)N3[C@H](CNC(=O)C4=C5C(OC=C5)=CC=C4)CCCC3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Faedo S, et al. Functional and binding kinetic studies make a distinction between OX1 and OX2 orexin receptorantagonists. Eur J Pharmacol. 2012 Oct 5;692(1-3):1-9.
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