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SB-674042

SB-674042

T16854
TargetMol Chemicals
CAS Number483313-22-0
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Product group Chemicals
Molecular Weight448.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SB-674042
  • Delivery Days Customer
    9
  • CAS Number
    483313-22-0
  • Category Supplier
    Chemical
  • Chemical Name
    SB-674042
  • Molecular Formula
    C24H21FN4O2S
  • Molecular Weight
    448.51
  • Scientific Description
    SB-674042 is an effective and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM). It exhibits 100-fold selectivity for OX1 over OX2 receptors.
  • Shelf life instruction
    3 years
  • SMILES
    C(=O)(C1=C(SC(C)=N1)C2=C(F)C=CC=C2)N3[C@H](CC=4OC(=NN4)C5=CC=CC=C5)CCC3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Malherbe, Pari; Borroni, Edilio; Pinard, Emmanuel et al. Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists. Molecular Pharmacology (2009), 76(3), 618-631.
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