Chemical Structure
Chemical Structure
SB204990 [154566-12-8]
AG-CR1-3697
Overview
- SupplierAdipoGen Life Sciences
- Product NameSB204990 [154566-12-8]
- Delivery Days Customer10
- CAS Number154566-12-8
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC18H22Cl2O5
- Molecular Weight389.3
- Scientific DescriptionChemical. CAS: 154566-12-8. Formula: C18H22Cl2O5. MW: 389.3. Potent ATP citrate lyase (ACLY) inhibitor. ATP citrate lyase (ACLY), a key enzyme for lipid synthesis, is frequently overexpressed or activated in cancer to promote lipid synthesis and tumor progression. Cell permeable prodrug form of SB201076. Hypolipidemic agent. Fatty acid synthesis and cholesterol synthesis inhibitor in a dose-dependent manner. Useful agent for immunometabolism research. Orally active in vivo. Shown to block fatty acid synthesis and cancer cell growth in pre-clinical studies. - Potent ATP citrate lyase (ACLY) inhibitor. ATP citrate lyase (ACLY), a key enzyme for lipid synthesis, is frequently overexpressed or activated in cancer to promote lipid synthesis and tumor progression. Cell permeable prodrug form of SB201076. Hypolipidemic agent. Fatty acid synthesis and cholesterol synthesis inhibitor in a dose-dependent manner. Useful agent for immunometabolism research. Orally active in vivo. Shown to block fatty acid synthesis and cancer cell growth in pre-clinical studies.
- SMILESO=C1[C@](CC(O)=O)(O)C[C@@H](CCCCCCC2=CC=C(Cl)C=C2Cl)O1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200