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Chemical Structure
Chemical Structure
Chemical Structure

SB366791 [472981-92-3]

Research Use Only
AG-CR1-0034
AdipoGen Life Sciences
CAS Number472981-92-3
Product group Chemicals
Estimated Purity>99% (NMR)
Molecular Weight287.8
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Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    SB366791 [472981-92-3]
  • Delivery Days Customer
    10
  • CAS Number
    472981-92-3
  • Certification
    Research Use Only
  • Estimated Purity
    >99% (NMR)
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C16H14ClNO2
  • Molecular Weight
    287.8
  • Scientific Description
    Chemical. CAS: 472981-92-3. Formula: C16H14ClNO2. MW: 287.8. Potent and selective TRPV1 antagonist. Glutamatergic synaptic transmission inhibitor. - Potent and selective TRPV1 antagonist [1, 2]. Glutamatergic synaptic transmission inhibitor [3].
  • SMILES
    COC1=CC=CC(NC(=O)C=CC2=CC=C(Cl)C=C2)=C1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist: M.J. Gunthorpe, et al.; Neuropharmacology 46, 133 (2004)
  • Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat: A. Varga, et al.; Neurosci. Lett. 385, 137 (2005)
  • TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation: S.C. Lappin, et al.; Eur. J. Pharmacol. 540, 73 (2006)