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SBI-581

HY-139439
MedChem Express
Estimated Purity98.83
DownloadMSDS
Product group Chemicals
Molecular Weight383.44
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SBI-581
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.83
  • Molecular Formula
    C24H21N3O2
  • Molecular Weight
    383.44
  • Scientific Description
    SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor, with an IC 50 of 42 nM. SBI-581 promotes TKS5alpha accumulation at RAB11-positive vesicles. SBI-581 inhibits invadopodia formation. SBI-581 shows reasonable pharmacokinetics in mice using IP injection. SBI-581 shows antitumor activity [1] . SBI-581 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    O=C1/C(C2=C(C=CC=C2C#CC3(O)CCNCC3)N1)=C\C4=CC5=C(N4)C=CC=C5
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200