SC-236

MedChem Express

SC-236 [170569-86-5]

10

170569-86-5

Research Use Only

99.56

C16H11ClF3N3O2S

401.79

SC-236 is an orally active COX-2 specific inhibitor ( IC 50 = 10 nM) and a PPARgamma agonist. SC-236 suppresses activator protein-1 ( AP-1 ) through c-Jun NH2-terminal kinase. SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model [1] [2] [3] [4] [5] .

O=S(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC=C(Cl)C=C3)C=C1)(N)=O

-20°C

12352200