SCAL-255 [2798953-61-2]

MedChem Express

SCAL-255 [2798953-61-2]

14

2798953-61-2

Research Use Only

99.15

C27H28F3N5O3

527.54

SCAL-255 is a potent mitochondrial complex I (CI) inhibitor with an IC50 of 1.14 microM. SCAL-255 blocks mitochondrial function, inhibits oxygen consumption rate (OCR), induces reactive oxygen species (ROS) production, and reduces MMP. SCAL-255 can be used in the research of oxidative phosphorylation (OXPHOS)-dependent cancers, such as colorectal cancer (CRC) and acute myeloid leukemia (AML), etc[1].

O=C(C1=NN(CC2=CC=CC(N3CCN(C(C4CC4)=O)CC3)=C2)C(C)=C1)NC5=CC=C(OC(F)(F)F)C=C5

-20°C,2°C to 8°C

12352200