SCN11A Polyclonal Antibody
RD76557A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSCN11A
Overview
- SupplierReddot Biotech
- Product NameSCN11A Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID11280
- Target nameSCN11A
- Target descriptionsodium voltage-gated channel alpha subunit 11
- Target synonymsFEPS3; HSAN7; NaN; NAV1.9; peripheral nerve sodium channel 5; PN5; SCN12A; sensory neuron sodium channel 2; SNS-2; sodium channel protein type 11 subunit alpha; sodium channel protein type XI subunit alpha; sodium channel, voltage-gated, type XI, alpha polypeptide; sodium channel, voltage-gated, type XI, alpha subunit; sodium channel, voltage-gated, type XII, alpha polypeptide; voltage-gated sodium channel subunit alpha Nav1.9
- HostRabbit
- IsotypeIgG
- Scientific DescriptionVoltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203