SCN5A Polyclonal Antibody

Reddot Biotech

SCN5A Polyclonal Antibody

5

0.3 mg/ml

SCN5A

sodium voltage-gated channel alpha subunit 5

cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; sodium channel protein cardiac muscle subunit alpha; sodium channel protein type 5 subunit alpha; sodium channel, voltage-gated, type V, alpha subunit; SSS1; VF1; voltage-gated sodium channel subunit alpha Nav1.5

The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.

-20°C

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