SDF1 beta antibody

GeneTex

SDF1 beta antibody

9

CXCL12 in transfected cells

For WB: Use at a dilution of 1:1,000. For IP: Use at a dilution of 1:300 - 1:500. For IHC: Use at a dilution of 1:100 - 1:500. Optimal dilutions/concentrations should be determined by the end user.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Cxcl12

chemokine (C-X-C motif) ligand 12

12-O-tetradecanoylphorbol 13-acetate repressed protein 1; PB; Pbsf; PBSF/SD; pre-B-cell growth-stimulating factor; Scyb1; Scyb12; Sdf; SDF-; Sdf1; stromal cell-derived factor 1; thymic lymphoma cell-stimulating factor; TLS; Tlsf; TP; Tpar1

Rabbit

IgG

CXCL12, Stromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).

Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203