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SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL [26628-22-8]

SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC042382
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetSDHB
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Overview

  • Supplier
    Biotium
  • Product Name
    SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SDHB/2382
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID6390
  • Target name
    SDHB
  • Target description
    succinate dehydrogenase complex iron sulfur subunit B
  • Target synonyms
    CWS2; IP; iron-sulfur subunit of complex II; MC2DN4; PGL4; SDH; SDH1; SDH2; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP21912
  • Protein Name
    Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • Scientific Description
    Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation. Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203