![SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL [26628-22-8] SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-818.jpeg)
SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC042382
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetSDHB
Overview
- SupplierBiotium
- Product NameSDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSDHB/2382
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID6390
- Target nameSDHB
- Target descriptionsuccinate dehydrogenase complex iron sulfur subunit B
- Target synonymsCWS2; IP; iron-sulfur subunit of complex II; MC2DN4; PGL4; SDH; SDH1; SDH2; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- HostMouse
- IsotypeIgG2b
- Protein IDP21912
- Protein NameSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- Scientific DescriptionSuccinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation. Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203