Assays

Reactivity

ELISA

Applications

AdipoGen Life Sciences

Supplier

Research Use Only

Certification

Business Unit

AG-45A-0043Y | Progranulin (rat) ELISA Kit | AdipoGen Life Sciences products available at Bio-Connect

Progranulin (rat) ELISA Kit... | AG-45A-0043Y | AdipoGen Life Sciences

Progranulin (rat) ELISA Kit

ELISA Assay. Detects rat progranulin. Does not cross-react with human progranulin. Colorimetric assay. Sample Types: Cell Culture Supernatant, Serum. Range: 0.063 to 4ng/ml. Sensitivity: 40pg/ml. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimers disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. - Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimers disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

Website

Events

Promotions

Our company

Our team

For suppliers

Vacatures

About us

Headquarters

Customer Service

Technical support

Accountmanagers

Contact

Our people

Antibodies

Chemicals

Proteins / Signaling Molecules

(Cell) Culture

Products

Our Company

Suppliers

Divisions

News

Bio-Connect

Biotech, Pharma & CRO

Academia

Diagnostics

Environment

Food

Veterinary

Industries

Disclaimer

Privacy Statement

Terms and conditions

Are you looking for specific products, alternatives, documentation or need assistance with solving product related issues? Let our in-house technical support team help you.

We support your research

<p>For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.</p>

Support your research

DNA / RNA / Vectors

Cell Culture

Genome Editing and Engineering

Molecular Biology

Lysates / Extracts

Expression

Labware / Accesories

Body Products

Technique Specific Products

Arrays / Slides

Diagnostic

Biologicals

Life Sciences

Services

Become a partner

Call +31 (0)26 326 44 50

Search results: AG-45A-0043Y

Didn't find what you were looking for?