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CD135 Antibody / FLT3 is validated for IHC. Biorbyt is available at Bio-Connect

CD135 Antibody / FLT3 antibody | ORB639658 | Biorbyt

CD135 Antibody / FLT3

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

FLT3 antibody is validated for IHC, IHC-P & tested in Human. Biorbyt is available at Bio-Connect

FLT3 antibody antibody | ORB607336 | Biorbyt

FLT3 antibody

Mouse monoclonal antibody to Flt3 / CD135

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