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MedChem Express

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1570231-89-8

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HY-125593 | APG-1387 [1570231-89-8] | Purity: 99.13% | MW: 1157.4 | Formula: C60H72N10O10S2 | MedChem Express is available at Bio-Connect

APG-1387 [1570231-89-8] | HY-125593 | MedChem Express

Dasminapant

Dasminapant (APG-1387), a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP-1, cIAP-2, and ML-IAP). Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma[1][2][3][4][5].

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Bio-Connect offers a wide range of chemicals that includes biochemicals, click chemistry products, inhibitors, small molecules and many more.

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