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Sandwich ELISA analysis of monkey IL-13 protein using GTX02960 IL13 antibody [IL13-I] as coating antibody and GTX02959-02 IL13 antibody [IL13-3] (Biotin) as detecting antibody. Substrate : pNPP

IL13 antibody [IL13-I] is validated for ELISA & tested in Human, Monkey. GeneTex is available at Bio-Connect

IL13 antibody [IL13-I] antibody | GTX02960 | GeneTex

IL13 antibody [IL13-I]

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]

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