Bio-Connect

SEC31A Polyclonal Antibody

RD268016A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSEC31A
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    SEC31A Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID22872
  • Target name
    SEC31A
  • Target description
    SEC31 homolog A, COPII coat complex component
  • Target synonyms
    ABP125; ABP130; HSPC275; HSPC334; NEDSOSB; protein transport protein Sec31A; SEC31 homolog A, COPII coating complex component; SEC31L1; SEC31-like protein 1; SEC31-related protein A; web1-like protein; yeast Sec31p homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203