Secalonic acid D

MedChem Express

Secalonic acid D

10

Research Use Only

C32H30O14

638.57

Secalonic acid D is a toxic compound against tumor cells. Secalonic acid D can be isolated from the metabolites of Aspergillus aculeatus . Secalonic acid D activates GSK3-beta , and degrades beta-catenin . Thus, Secalonic acid D down-regulates c-Myc expression, arrests cell cycle at G1 phase, induces cell apoptosis [1] [2] .

COC([C@]12C(C(C3=C(O)C(C4=CC=C(O[C@@]5(C(C6=O)=C(C[C@@H]([C@H]5O)C)O)C(OC)=O)C6=C4O)=CC=C3O1)=O)=C(C[C@@H]([C@H]2O)C)O)=O

12352200