Immunohistochemistry of paraffin-embedded Human liver damage using SECISBP2 Polyclonal Antibody at dilution of 1:200 (40x lens).
SECISBP2 Polyclonal Antibody
E-AB-61334
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSECISBP2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
- UNSPSC12352203