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Seliciclib

Seliciclib

T2095
TargetMol Chemicals
CAS Number186692-46-6
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Product group Chemicals
Molecular Weight354.45
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Seliciclib
  • Delivery Days Customer
    4
  • CAS Number
    186692-46-6
  • Category Supplier
    Chemical
  • Chemical Name
    Seliciclib
  • Molecular Formula
    C19H26N6O
  • Molecular Weight
    354.45
  • Scientific Description
    Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E (IC50: 0.1 uM). It also inhibits Cdk7/cyclin H, Cdk5/p35, and Cdc2/cyclin B (IC50s: 0.49/0.16/0.65 uM).
  • Shelf life instruction
    3 years
  • SMILES
    C(C)(C)N1C=2C(=C(NCC3=CC=CC=C3)N=C(N[C@H](CC)CO)N2)N=C1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Pippin JW, et al. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist. J Clin Invest. 1997 Nov 15;100(10):2512-20.
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