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Selisistat R-enantiomer

Selisistat R-enantiomer

T15263
TargetMol Chemicals
CAS Number848193-69-1
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Product group Chemicals
Molecular Weight248.71
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Selisistat R-enantiomer
  • Delivery Days Customer
    4
  • CAS Number
    848193-69-1
  • Category Supplier
    Chemical
  • Chemical Name
    Selisistat R-enantiomer
  • Molecular Formula
    C13H13ClN2O
  • Molecular Weight
    248.71
  • Scientific Description
    Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 uM).
  • Shelf life instruction
    3 years
  • SMILES
    C(N)(=O)[C@H]1C2=C(C=3C(N2)=CC=C(Cl)C3)CCC1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
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