Selitrectinib (LOXO-195) [2097002-61-2]
S8636
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameSelitrectinib (LOXO-195) [2097002-61-2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionSelitrectinib (LOXO-195, BAY 2731954) is an orally available, highly potent, and selective TRK kinase inhibitor with low nanomolar inhibitory activity against TRKA G595R, TRKC G623R, and TRKA G667C, IC50s ranging from 2.0 to 9.8 nmol/L. It is more than 1,000-fold selective for 98% of non-TRK kinases tested.
- UNSPSC12352200