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Selitrectinib

T7435
TargetMol Chemicals
CAS Number2097002-61-2
Product group Chemicals
Molecular Weight380.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Selitrectinib
  • Delivery Days Customer
    4
  • CAS Number
    2097002-61-2
  • Category Supplier
    Chemical
  • Chemical Name
    Selitrectinib
  • Molecular Formula
    C20H21FN6O
  • Molecular Weight
    380.42
  • Scientific Description
    Selitrectinib (LOXO-195) is a potent and selective inhibitor of the receptor tyrosine kinases(TRK)( TrkA and TrkC with IC50s of 0.6 and <2.5 nM, respectively)
  • Shelf life instruction
    3 years
  • SMILES
    FC=1C=C2[C@@]3(N(C4=NC=5N(C=C4)N=CC5C(=O)N[C@H](C)CCC2=NC1)CCC3)[H]
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Qin Q, Fu Q, Wang X, et al.Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors.European Journal of Medicinal Chemistry.2023: 115291.