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Selonsertib (hydrochloride)

HY-18938A
MedChem Express
CAS Number1448428-05-4
Product group Chemicals
Molecular Weight481.95
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Selonsertib (hydrochloride)
  • Delivery Days Customer
    9
  • CAS Number
    1448428-05-4
  • Certification
    Research Use Only
  • Molecular Formula
    C24H25ClFN7O
  • Molecular Weight
    481.95
  • Scientific Description
    Selonsertib hydrochloride (GS-4997 hydrochloride) is an orally bioavailable enzyme inhibitor with potential anti-inflammatory, anti-tumor and anti-fibrotic activities. Selonsertib hydrochloride blocks ASK1 phosphorylation and activation by binding to the catalytic kinase domain. Selonsertib hydrochloride prevents the production of inflammatory cytokines and reduces the expression of genes associated with fibrosis. Selonsertib hydrochloride inhibits excessive apoptosis and limits cell proliferation [1] .
  • SMILES
    O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F.Cl
  • UNSPSC
    12352200

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Chemical Structure
Product group Chemicals
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