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SEMA3C Polyclonal Antibody

RD82112A
Reddot Biotech
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityMouse, Rat
TargetSEMA3C
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    SEMA3C Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence, Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10512
  • Target name
    SEMA3C
  • Target description
    semaphorin 3C
  • Target synonyms
    sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; sema E; SEMAE; semaphorin E; semaphorin-3C; SemE
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203