SEMA3C Polyclonal Antibody
RD82112A
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityMouse, Rat
TargetSEMA3C
Overview
- SupplierReddot Biotech
- Product NameSEMA3C Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10512
- Target nameSEMA3C
- Target descriptionsemaphorin 3C
- Target synonymssema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; sema E; SEMAE; semaphorin E; semaphorin-3C; SemE
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203