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Senexin A [1366002-50-7]

Research Use Only
HY-15681
MedChem Express
CAS Number1366002-50-7
Product group Chemicals
Estimated Purity99.79
Molecular Weight274.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Senexin A [1366002-50-7]
  • Delivery Days Customer
    10
  • CAS Number
    1366002-50-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.79
  • Molecular Formula
    C17H14N4
  • Molecular Weight
    274.32
  • Scientific Description
    Senexin A is an inhibitor of CDK8/19 (IC50: 280 nM, CDK8) and an inhibitor downstream of p21 transcription. It only inhibits p21-induced transcription but does not inhibit other biological effects of p21. Senexin A inhibits CMV-GFP induction as well as the p21 stimulatory activity of the consensus NF-kappaB-dependent promoters[1][2].
  • SMILES
    N#CC1=CC=C2C(C(NCCC3=CC=CC=C3)=NC=N2)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200