SERCA1 ATPase antibody, N-term

GeneTex

SERCA1 ATPase antibody, N-term

9

WB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

ATP2A1

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

ATP2A; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; calcium pump 1; endoplasmic reticulum class 1/2 Ca(2+) ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA1; SR Ca(2+)-ATPase 1

Rabbit

IgG

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013]

Human, Monkey

-20°C or -80°C,2°C to 8°C

12352203