SERPINI1 Polyclonal Antibody
RD266541A
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetSERPINI1
Overview
- SupplierReddot Biotech
- Product NameSERPINI1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5274
- Target nameSERPINI1
- Target descriptionserpin family I member 1
- Target synonymsHNS-S1; HNS-S2; neuroserpin; peptidase inhibitor 12; PI12; PI-12; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; truncated HNS-T
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203