Serpinin

MedChem Express

Serpinin

5

Research Use Only

Serpinin is an agonist of the protease inhibitor Nexin-1 ( PN-1 ). Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function [1] . Serpinin is a selective agonist for beta-adrenergic receptors . Serpinin interacts with beta1-adrenergic receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects [2] .

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