Serum Amyloid P / APCS(APCS/3240), CF594 conjugate, 0.1mg/mL [26628-22-8]

Biotium

Serum Amyloid P / APCS(APCS/3240), CF594 conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

APCS/3240

0.1 mg/ml

Other Conjugate

APCS

amyloid P component, serum

9.5S alpha-1-glycoprotein; epididymis secretory sperm binding protein Li 92n; HEL-S-92n; pentaxin-related; pentraxin-2; pentraxin-related; PTX2; SAP; serum amyloid P-component

Mouse

IgG2b

Serum amyloid P-component

Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimers disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human

2°C to 8°C

12352203