Setileuton

MedChem Express

Setileuton

5

Research Use Only

C22H17F4N3O4

463.38

Setileuton (MK-0633) is an inhibitor for 5-lipoxygenase , that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC 50 of 3.9 and 52 nM, respectively [1] .

O=C1C=C(C2=CC=C(C=C2)F)C3=CC=C(CNC4=NN=C([C@](CC)(O)C(F)(F)F)O4)C=C3O1

12352200