SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated

TargetMol Chemicals

SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated

16

Research Use Only

100.7 kDa (predicted). Due to glycosylation, the protein migrates to 170-200 kDa based on Tris-Bis PAGE result.

Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the beta-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 100.7 kDa and the accession number is Q53EL9-1.

-20°C

12352200