SFRP1 Antibody, FITC conjugated

Cusabio

SFRP1 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

SFRP1

secreted frizzled related protein 1

frizzled-related protein; FRP; FRP1; FRP-1; FrzA; SARP2; SARP-2; secreted apoptosis-related protein 2; secreted frizzled-related protein 1; sFRP-1

Rabbit

IgG

Secreted frizzled-related protein 1

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Human

-20°C or -80°C

12352203