SH3BP2 Polyclonal Antibody
RD265749A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSH3BP2
Overview
- SupplierReddot Biotech
- Product NameSH3BP2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6452
- Target nameSH3BP2
- Target descriptionSH3 domain binding protein 2
- Target synonyms3BP2; 3BP-2; Abl-SH3 binding protein 2; CRBM; CRPM; epididymis secretory sperm binding protein; RES4-23; SH3 domain-binding protein 2; TNFAIP3 interacting protein 2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203